Which medication should the nurse prepare to administer to a client showing signs of warfarin overdose?

• A. Vitamin K.
• B. Metoprolol.
• C. Protamine sulfate.
• D. Amiodarone.

Answer: (A)

In cases of warfarin overdose, the administration of Vitamin K is the appropriate intervention. Warfarin is an anticoagulant that works by inhibiting vitamin K dependent clotting factors, which are essential for normal blood coagulation. When a patient exhibits signs of warfarin overdose, such as excessive bleeding or an elevated International Normalized Ratio (INR), administering Vitamin K can help reverse the effects of warfarin by replenishing the vitamin K that is necessary for synthesizing clotting factors.

Vitamin K can be given orally or intravenously, depending on the severity of the overdose and the clinical situation. It essentially allows the body to produce new clotting factors, which aids in restoring hemostasis. Immediate and appropriate treatment with Vitamin K helps mitigate the risks associated with excessive anticoagulation, thereby stabilizing the patient's condition.

Other options, while they may have roles in different contexts, are not indicated for reversing warfarin overdose. Metoprolol is a beta-blocker primarily used for hypertension and heart-related issues. Protamine sulfate is an antidote for heparin, not warfarin. Amiodarone is an antiarrhythmic medication used to treat certain types of cardiac dysrhythmias. Thus